Contributions of marine invertebrates to our understanding of human health and disease
Hamdoun, A.; DeTomaso, A.W.; Foltz, K. (2023). Contributions of marine invertebrates to our understanding of human health and disease, in: Fleming, L.E et al. Oceans and human health: Opportunities and impacts. pp. 181-201. https://dx.doi.org/10.1016/b978-0-323-95227-9.00015-4
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| Keywords |
Developmental biology
Immunology
Pharmacology
Reproduction
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| Author keywords |
Biomedical models; Neuroscience; Sea urchin |
| Authors | | Top |
- Hamdoun, A.
- DeTomaso, A.W.
- Foltz, K.
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| Abstract |
Within the ocean is the greatest diversity of biological innovations on the planet. They represent a treasure trove of potential solutions to challenges in the environment and human health. Much of this is captured within the marine invertebrates, a group of multicellular animals that spans close relatives to humans to our most distantly related animal ancestors. For centuries these animals have been used for biological study, contributing to our fundamental understanding of human cellular physiology, neurobiology, and development. Today innovations in functional and descriptive genomics, as well as in methods of culturing, imaging, and biochemistry, are fueling a second transformation in marine invertebrate research. This transformation is extending work into new animals with useful biological features, as well as enabling new lines of research in established marine invertebrate model species. In this chapter, we review how these animals have informed our understanding of diverse human disease-relevant pathways. |
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